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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRWD1 All Species: 11.82
Human Site: S2157 Identified Species: 26
UniProt: Q9NSI6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSI6 NP_061836.2 2320 262920 S2157 R P D T S S K S S D L G S V T
Chimpanzee Pan troglodytes XP_001170924 2320 262999 S2157 R P D T S S K S S D L G S V T
Rhesus Macaque Macaca mulatta XP_001108655 2320 262912 S2157 R P D T S S K S S D L G S V T
Dog Lupus familis XP_544889 2401 270094 S2238 G P D P G P K S D S E L V S V
Cat Felis silvestris
Mouse Mus musculus Q921C3 2304 259007 S2149 P K A S D L G S V T D S D V D
Rat Rattus norvegicus XP_001054667 1799 202807 P1647 S K F I Q T R P K R K L R R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510724 2599 293992 A2178 S E S E S M E A S E T A G S A
Chicken Gallus gallus XP_416730 2299 260504 K2144 T I R R A R N K R S R A P L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920441 2191 247687 S2036 K R K H G G S S E S D A D S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395863 1676 190205 V1524 A R K T V P S V S A D S D S G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201169 1837 210307 I1685 R L R S G T D I N S N E G S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.9 85.7 N.A. 78.7 44.7 N.A. 65.6 61.8 N.A. 44.7 N.A. N.A. 34.9 N.A. 27.3
Protein Similarity: 100 99.7 98.7 89.7 N.A. 86.1 57.7 N.A. 74.3 73.4 N.A. 61.4 N.A. N.A. 49.4 N.A. 42.3
P-Site Identity: 100 100 100 26.6 N.A. 13.3 0 N.A. 13.3 0 N.A. 6.6 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 20 13.3 N.A. 33.3 13.3 N.A. 13.3 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 10 0 0 10 0 10 0 28 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 37 0 10 0 10 0 10 28 28 0 28 0 10 % D
% Glu: 0 10 0 10 0 0 10 0 10 10 10 10 0 0 10 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 28 10 10 0 0 0 0 28 19 0 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 10 19 19 0 0 0 37 10 10 0 10 0 0 0 19 % K
% Leu: 0 10 0 0 0 10 0 0 0 0 28 19 0 10 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 10 0 10 0 0 0 0 % N
% Pro: 10 37 0 10 0 19 0 10 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 37 19 19 10 0 10 10 0 10 10 10 0 10 10 0 % R
% Ser: 19 0 10 19 37 28 19 55 46 37 0 19 28 46 0 % S
% Thr: 10 0 0 37 0 19 0 0 0 10 10 0 0 0 28 % T
% Val: 0 0 0 0 10 0 0 10 10 0 0 0 10 37 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _